Multiple Choice Questions (MCQ) on Veterinary Pathology (Part-3)

Multiple Choice Questions

1. Dermatitis may be produced by the action of sunlight on certain photodynamic substances that may be present in skin is known as:
   a. Sensitization b. Photosensitization c. Frost bite d. None

2. Fat in the cells and tissues are usually stained by:
a. Osmic acid b. Sudan III and IV c. Oil red O d. All

3. Presence of fat on the ventricular endocardium gives it a speckled appearance and it is called:
a. Fatty infiltration b. Fatty degeneration c. Thrush breast heart d. None

4. In Xanthomas, the macrophage are laden with:
a. Glycogen b. Haemosiderin c. Cholesterol d. Fat

5. To demonstrate glycogen, tissue must be preserved in the
a. 10% formalin b. Formal saline c. Neutral buffered saline d. Absolute alcohol

6. Deposition of carbon particles in lung is referred as:
a. Silicosis b. Siderosis c. Anthracosis d. Pneumoconiosis

7. ……………. is the most common disturbance of cell metabolism and is the first reaction of cell to injury:
a. Fatty change b. Hydropic degeneration c. Mucinous degeneration d. Albuminous degeneration

8. Brain sand is a ……….. type of hyaline change:
a. Keratohyaline b. Cellular hyaline c. Connective tissue hyaline d. None

9. Main target organ in Aflatoxicosis is
a. Liver b. Spleen c. Heart d. Lungs

10. In ICH, inclusion body is found in hepatocytes in location of:
a. Cytoplasm b. Nucleus c. Both a and b d. None

11. In Rabies, Brain lesion reveals:
a. Suppurative encephalitis b. Non- Suppurative encephalitis
c. Both a and b d. None

12. Farcy is
a. Acute form of Actinomycosis b. Cutaneous form of Glander
c. Subacute form of CBPP d. Chronic form of CBPP

13. Nasal Polyps are caused by:
a. Schistosoma nasalis b. E. coli c. Rhinosporidium seebere d. Mycoplasma mycoides

14. Summer Mastitis is caused by:
a. Staphylococcus aureus b. Streptococcus uberis c. Corynebacterium pyogens d. Candida albicans

15. In Pox, there is
a. Hyperkeratosis only b. Acanthosis and parakeratosis
c. Acanthosis and hyperkeratosis d. Acanthosis, Parakeratosis and Hyperkeratosis

16. Diabetes insipidus is under the influence of hormone released from :
a. Anterior pituitary b. Posterior pituitary c. Pancreas d. All

17. Metaplasia of esophageal gland in poultry occurs due to the deficiency of:
a. Vit-A b. Vit -D c. Vit- C d. All

18. Local dilation of Artery is known as:
a. Aneurysm b. Ball thrombi c. Arteritis d. None

19. Spirocerca lupi may form ……………. in the esophagus
a. Tumor b. Granulomatous lesion c. Abscess d. Dentigerous cyst

20. 80 degree or more rotation of the intestine on the long axis of mesentery is called:
a. Torsion b. Intussuseption c. Volvulus d. None

21. Glycogen infiltration occurs due to disturbance in ……….. metabolism
a. Protein b. Mineral c. Fat d. Carbohydrate

22. Inflammation of tongue is known as:
a. Glossitis b. Stomatitis c. Proctitis d. gingivitis

23. A malignant tumor of endothelium of blood vessel is known as:
a. Angioma b. Angiosarcoma c. Lymphangioma d. Leiomyoma

24. Melena is the presence of blood in …
a. Vomit b. Stool c. Urine d. All

25. Immunologically mediated glomerulonephritis does not occurs in:
a. Chronic Hog Cholera b. Aleutian disease c. Equine infectious anemia d. Canine Distemper

26. Principle Immunoglobulin associated with delayed hypersensitivity reaction is:
a. IgG b. Ig E c. IgG and IgM d. None

27………. is the inflammation of hip joint
a. Coxitis b. Arthritis c. Gonitis d. Spavin

28. Accumulation of edema fluid in the abdominal cavity is called:
a. Ascites b. Anasarca c. Peritonitis d. All

29. Movement of cells from axial stream to wall of the vessel is known as:
a. Axial flow b. Reversed axial flow c. Inflammed vessel d. Both b and c

30. Removal of the dead neurons by microglial and oligodendroglial cells is known as:
a. Neuronophagia b. Satellitosis c. Shrinkage d. Chromatolysis

Correct Answers

1.

b. (Photosensitization)
Dermatitis may be produced by the action of sunlight on certain photodynamic substances that may be present in skin, known as Photosensitization
Frost Bite: Injury caused by freezing of skin

2.

d. (All)
Fat in the cells and tissue are usually stained by:
Osmic acid: Crystalline oxide of osmium that is volatile, caustic and strong oxidizing agents, used as stain for Neutral fat and myelin and as a general fixative for electron microscopy.
Sudan III and IV:: Sudan III is Lysochrome diazo dye, structurally related to azobenzene, used for lipid staining. Sudan IV, also called Scarlet red and fat Ponceau R, fat soluble dye, used for staining triglyceride, lipids and lipoprotein present in cells and tissue.
Oil red ‘O’: Lysochrome diazodye used for staining of neutral triglycerides and lipid on frozen sections and some lipoproteins on paraffin sections.

3.

a. (Fatty infiltration)
Presence of fat on the ventricular endocardium gives it a speckled (Small spot or patch) appearance - fatty infiltration
The Accumulation of fat globules within cells of an organ, such as liver or heart resulting in deterioration of tissue and diminished functioning of affected organ - Fatty degeneration
A condition of heart in which the inner surface of ventricular wall and papillary muscles are streaked and spotted seen in marked case of fatty degeneration - Thrush breast heart

4.

c. (Cholesterol)
In Xanthomas, the macrophages are laden with Cholesterol.
Xanthomas is a skin condition in which certain fats, build up under surface of skin. These are raised, waxy appearing yellowish colored skin lesion, associated with underlying cholesterol abnormality.

5.

d. (Absolute alcohol )
To demonstrate glycogen, tissue must be preserved in the absolute alcohol.

6.

c. (Anthracosis)
Deposition of carbon particle in lung - Anthracosis
Deposition of silicon in lung - Silicosis
Deposition of Iron in Lung - Siderosis
Deposition of Dust particles in lung - Pneumoconiosis

7.

d. (Albuminous degeneration)
Albuminous Degeneration is the most common disturbance of cell metabolism and is the first reaction of cell to injury.

8.

b. (Cellular hyaline )
Brain sand is a cellular hyaline type of hyaline change
Pineal gland contains characteristic, extracellular concretions ( consists of calcium phosphates and carbonates in an organic matrix, which is deposited in concentric layers), called Corpora arenacea or brain sand.

9.

a. (Liver)
Main target organ in Aflatoxicosis is Liver.
Aflatoxicosis, Ochratoxicosis and trichothecene mycotoxicosis are the most commonly seen mycotoxicosis seen in poultry.
Aflatoxin is most common, and highly toxic mycotoxins produced by fungus Aspergillus flavus, Aspergillus parasiticus, Penicillium puberulum.
Aflatoxins species: B1, B2, G1 and G2, out of which B1 is most toxic.
Ochratoxicosis is mycotoxicosis caused by ochratoxins of fungus Aspergillus ochraceus, 3 times more harmful than aflatoxin B1, majorly affect kidney. There are four types of Ochratoxins, A, B, C , D, out of which A is more toxic.
Trichothecene mycotoxicosis is mycotoxicosis caused by Trichothecene toxin includes T-2 toxin, diacetoxyscirpenol, Nivalenol, Deoxynivalenol etc., produced by Fusarium fungus. Mainly causes immunosuppression.

10.

b. (Nucleus)
In ICH, inclusion body is found in hepatocytes in location of Nucleus.
Inclusion Bodies: Abnormal or foreign cell/structure within a cell.
Intracytoplasmic Inclusion Bodies: Negri bodies ( Rabies), Guarnieri bodies ( Small pox), Paschen bodies ( Small pox), Bollinger bodies ( Fowl pox), Borrel bodies ( Fowl pox)
Acidophilic intranuclear inclusion bodies: Herpes, Polio Varicella zoster virus, Yellow fever
Basophilic Intranuclear inclusion bodies: Adeno virus
Both Intranuclear and intracytoplasmic inclusion bodies, found in Canine Distemper, Measles.

11.

b. (Non- Suppurative encephalitis)
In Rabies, Non- Suppurative Encephalitis is seen in Brain ( Gasserian ganglion, Hippocampus, Medulla oblongata, Cerebellum etc.) Impression smears made from these structures, when stained with Seller stain, Negri’s bodies are found.

12.

b. (Cutaneous form of Glander)
Glander ( Farcy, Malleus), highly contagious chronic disease of animals, characterized by formation of nodules and ulcers in upper respiratory tract, lungs and Cutaneous tissues, Caused by Gram- negative bacteria, Actinobacillus mallei.
Actinomycosis (Lumpy jaw),Chronic infectious disease, caused by Actinomyces bovis characterized by rarefying osteomyelitis of bone of skull in cattle and in pig by tumor like enlargement of mammary gland and in horse involvement of bursa of ligamentum nuchae.
Contagious Bovine Pleuro Pneumonia ( CBPP) is an acute, sub - acute, clinically inapparent, or chronic disease characterized by formation of massive pathological changes ( marked edema of interlobular septum, diffused pneumonia and serofibrinous pleuritis) in thoracic organs specially lungs and pleura, caused by Mycoplasma mycoides var. mycoides.

13.

c. (Rhinosporidium seebere)
Nasal polyps are soft, painless, noncancerous growths on the lining of nasal passages or sinus, hang down like teardrops or grapes, result from chronic inflammation and are associated with asthma, recurring infection, allergies, drug sensitivity or certain immune disorders and Rhinosporidium seebere infection.

14.

c. (Corynebacterium pyogens)
Summer Mastitis is caused by Corynebacterium pyogens.
Cold mastitis is caused by Leptospira spp.
Environmental mastitis is caused by E.coli, Streptococcus dysgalactia, Streptococcus uberis etc.
Contagious mastitis is caused by Staphylococcus aureus, Streptococcus agalactia etc.

15.

d. (Acanthosis, Parakeratosis and Hyperkeratosis)
Pox disease is viral disease caused by Orthopox ( Cow and Buffalo pox), Capripox ( Goat pox and sheep pox), Suipox ( Swine Pox) virus of family Pox viridae, characterized by Acanthosis ( Skin disorder that cause dark discoloration of skin), Parakeratosis ( It is a condition where skin cells get nucleated during keratinization) and hyperkeratosis ( It is condition where there is increased expression of keratin in skin cell).

Difference between Parakeratosis and Hyperkeratosis

16.

b. (Posterior pituitary)
ADH ( Antidiuretic hormones) secreted by Hypothalamus, released from Posterior Pituitary gland, acts on collecting duct of nephron of kidney, regulates water reabsorption and balance, whose deficiency leads to the Diabetes Insipidus ( polydipsia, Polyuria and Polyphagia).

17.

a. (Vit-A)
Metaplasia of Oesophageal glands in poultry occurs due to deficiency of Vit -A.

Deficiency Diseases of Poultry

18.

a. (Aneurysm)
Local dilation of Artery - Aneurysm
Inflammation of Artery - Arteritis
A common condition that develops when a sticky substance, called plaque builds up inside artery. It’s a medical disorder that damages lumen of arteries by plaque deposition. - Atherosclerosis
Arteriosclerosis is a disease that block the wall of arteries due to thickening of wall of vessel, occurs due to aging.

19.

b. (Granulomatous lesion)
Spirocerca lupi, Oesophageal worm, bright red worm, long, generally located within nodules in esophagus, gastric or aortic wall. Dogs get infection by eating an intermediate host ( Dung Beetle),or transport host ( Chicken, reptiles rodents). Lesions associated with Spirocerca infections are aneurysms of thoracic aorta, reactive granulomas of variable size around worm in esophagus.
Note: Dentigerous cyst are common type of odontogenic cysts ( Fluid - filled sac that develops in jaw bone over a tooth that has not erupted yet.

20.

a. (Torsion)
Intestinal torsion is the twisting of the bowel on it’s longitudinal axis, causing luminal obstruction while Intestinal volvulus is twisting of the bowel on it’s mesenteric axis.
Intussusception: Inversion of one portion of intestine within another.

21.

d. (Carbohydrate)
Glycogen infiltration occurs due to disturbance in carbohydrate metabolism.

Degenerative changes due to following Disturbance:

• Protein metabolism -Cloudy swelling or parenchymatous/albuminous degeneration, Hydropic degeneration, hyaline degeneration, mucinous degeneration, Amyloid infiltration, Fibrinoid degeneration
• Carbohydrate metabolism - Glycogen infiltration
• Fat metabolism- fatty degeneration, fatty infiltration, obesity

22.

a. (Glossitis)

Anatomical Terminologies of Inflammation

23.

b. (Angiosarcoma)

Classification of Tumor

24.

• b. (Stool)
• Epistaxis - blood from nose
• Hematemesis - Blood in Vomit
• Hemoptysis- Blood in sputum
• Enterorrhagia- Bleeding from intestine
• Hematuria- Blood in Urine
• Hemothorax- Blood in the thoracic cavity
• Hemopericardium- Blood in the pericardium
• Hemosalpinx - Bleeding in Oviducts

25.

d. (Canine Distemper)
Except Canine Distemper, all diseases in options, Chronic Hog cholera, Aleutian disease and Equine Infectious anemia, immunologically mediated glomerulonephritis i.e., Immune complex (Antigen - antibody complex) formed during these disease causes inflammatory response in Glomerulus i.e., Glomerulonephritis.
Note: Aleutian disease, also known as mink plasmacytosis, is a disease which causes spontaneous abortion and death in mink and ferrets, caused by Carnivore amdoparvovirus 1

26.

d. (None)

• Type IV (Delayed type) hypersensitivity reaction is mediated by Cellular response.
• Type - I hypersensitivity reaction is mediated by IgE antibodies
• Type -II hypersensitivity reaction (Cytotoxic reaction) mediated by IgG or IgM antibodies
• Type -III hypersensitivity reaction mediated by immune complex
• Type -IV hypersensitivity (delayed type) mediated by cellular response.

27.

a. (Coxitis)

• Coxitis is the inflammation of hip joint.
• Gonitis is the inflammation of knee joint
• Spavin is the degenerative, non- septic arthritis of hock joint, characterized by appearance of three characteristic swelling.
• omarthritis: inflammation of shoulder joint.
• Carpitis/Popped knee: Inflammation of carpal joint.
• Quittor: Purulent inflammation of collateral cartilage of coffin joint.
• Pedal osteitis: Inflammation of III phalanx

28.

a. (Ascites)
Accumulation of edema fluid in the abdominal cavity - Ascites
Generalized accumulation of serous fluid in the interstitial space of whole body - Anasarca
Inflammation of Peritoneum - Peritonitis

29.

d. (Both b and c)
-Movement of cells from axial stream to wall of the vessel is known as Reversed axial flow ( Inflammed vessel)

30.

a. (Neuronophagia)
Removal of the dead neurons by microglial and oligodendroglial cells is known as Neuronophagia.
Satellitosis: Usually abnormal clustering of one type of cell around another especially the clustering of glial cells around neuron in brain during pathological state.

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